Sol-20 Terminal Computer (1976)
This was for the first time I could see a real S-100-bus computer. SOL-20 was an interesting piece of engineering and integrated all basic components inside a compact chassis. Although intended to be just a terminal this is a fully fledged Intel 8080-based personal computer with five S-100 bus slots for user expansion.
I would like to recommend really nice web pages about S-100 computers (see the whole site): http://www.s100computers.com/Hardware%20Folder/Processor%20Technology/History/History.htm
You can find a lot of interesting information and stories from the beginning of some software and hardware products (… did you know the early history of AutoCAD before it was ported to IBM PC?).
UPDATE: An article about S-100 computers: http://www.theregister.co.uk/2009/05/01/s100/?page=1